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Klebsiella pneumoniae : Introduction, pathogenecity, laboratory diagnosis
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Klebsiella pneumoniae 💦🩷 Encapsulated gram-negative rod that causes hospital-acquired pneumonia, especially in patients with ventilators, alcohol use disorder, or aspiration risk. Biochemical profile 🧪 Lactose fermenter (pink on MacConkey) Urease positive Citrate positive Indole negative Non-motile Produces thick, jelly-like sputum due to its polysaccharide capsule. Think “currant jelly sputum” when you hear Klebsiella pneumoniae. 🪼 🦠🔬Ready to pass the ASCP exam? Click the link in my bio o
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Hypervirulent Klebsiella pneumoniae (HvKP) has become a major pathogen that causes severe human infections such as pyogenic liver abscesses, pneumonia, and endophthalmitis. HvKP strains typically possess a thick, hypermucoid capsule and therefore produce mucoid colonies that generate a positive result in string test. HvKP exhibits features of enhanced virulence including production of a larger amount of capsule polysaccharide (CPS), ability to resist phagocytosis, and distant metastases. The cap
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