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Lesson on Acute Tubular Necrosis (ATN): Symptoms, Causes and Treatments. Acute Tubular Necrosis (ATN) is an abrupt decrease in GFR with increases in urea and creatinine levels due to ischemic or nephrotoxic injuries to renal tubules. ATN results in high FeNa and excretion of "muddy brown casts". The two main categories of causes of ATN are ...
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