Batrachotoxin | C31H42N2O6 | CID 6324647 - PubChem
Batrachotoxin | C31H42N2O6 | CID 6324647 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Batrachotoxin - Wikipedia
Batrachotoxin (BTX) is an extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word βάτραχος, bátrachos, 'frog'. [3] Structurally-related chemical compounds are often referred to …
1-[(1R,5R,6S,9S,12R)-9,12-dihydroxy-6,16-dimethyl-10,19-dioxa-16 ...
Oct 14, 2021 · Batrachotoxins (BTX) are extremely potent cardiotoxic and neurotoxic steroidal alkaloids found in poison dart frogs (genus Dendrobates and Phyllobates), Melyridae beetles, and certain birds (genus Pitohui and Ifrita). They act directly on sodium channels. (L1069). It is the most potent non-peptidal neurotoxin known. L1069: Wikipedia. Batrachotoxin.
Dual receptor-sites reveal the structural basis for ... - Nature
Mar 14, 2024 · Overall, our structure provides insight into batrachotoxin’s potency, efficacy, and multifaceted functional effects on voltage-gated sodium channels via a dual receptor site mechanism.
Batrachotoxin | C31H42N2O6 - ChemSpider
ChemSpider record containing structure, synonyms, properties, vendors and database links for Batrachotoxin
BATRACHOTOXIN Structure - C31H42N2O6 - Over 100 million chemical …
The 3D chemical structure image of BATRACHOTOXIN is based on the ball-and-stick model which displays both the three-dimensional position of the atoms and the bonds between them.
Batrachotoxin - an overview | ScienceDirect Topics
Empirical formula: C 22 H 28 O 5; molecular weight: 372.4. The solubility in water is 9.0 mg/l, and the log P is 4.3. Pure pyrethrin II is dextrorotatory: [ α ] D 20 =+ 14.7 ° (isooctane, ethyl ether).
Structure of batrachotoxin, a steroidal alkaloid from the …
May 1, 2002 · Structure of batrachotoxin, a steroidal alkaloid from the Colombian arrow poison frog, phyllobates aurotaenia, and partial synthesis of batrachotoxin and its analogs and homologs. Takashi Tokuyama, J. Daly, and ; B. Witkop
Batrachotoxin: Chemistry and Pharmacology | Science - AAAS
Batrachotoxin has been shown to be a pyrrolecarboxylic ester of a novel steroidal base with unique and selective actions on a variety of electrogenic membranes.
Batrachotoxin acts as a stent to hold open homotetrameric …
Batrachotoxin (BTX), an alkaloid from skin secretions of dendrobatid frogs, causes paralysis and death by facilitating activation and inhibiting deactivation of eukaryotic voltage-gated sodium (Nav) channels, which underlie action potentials in nerve, muscle, and heart.