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  1. Pathology Outlines - p40

    Jun 13, 2022 · p40 is a truncated, nontransactivating p63 isoform that may stimulate cell proliferation, block apoptosis and favor unrestrained tumor growth

  2. Pathology Outlines - Stains & CD markers

    Immunostains, routine stains and CD markers at PathologyOutlines.com

  3. Pathology Outlines - Squamous cell carcinoma

    Aug 8, 2023 · C. p40 is the stain of choice for the identification of squamous cell carcinoma and will help demonstrate squamous differentiation. Answers A and B are incorrect because while CK7 and CK5/6 …

  4. Pathology Outlines - Diffuse mesothelioma (pleura)

    Mar 4, 2021 · Expression of p40 Metastatic sarcomatoid carcinoma Expression of claudin 4 might be helpful Sarcoma (primary or metastatic) Lack of expression of keratin Expression of lineage specific …

  5. Pathology Outlines - Adenoid cystic carcinoma

    Jul 30, 2021 · Typically p63 positive / p40 negative, whereas adenoid cystic carcinoma is typically positive for both p63 and p40 (Am J Surg Pathol 2014;38:257) HPV related multiphenotypic …

  6. Pathology Outlines - NUT carcinoma

    Jan 21, 2025 · NUT carcinoma (see comment) Comment: Immunostains show that the tumor cells are positive for AE1 / AE3, p40 and NUT and negative for CD99 and synaptophysin with intact …

  7. Pathology Outlines - Adenoma

    p40 or CK5/6 may be very helpful in such cases; shows lack of basal cell layer Peribronchiolar metaplasia: Ill defined borders and is usually a multifocal process, often in the setting of interstitial …

  8. Pathology Outlines - Pleomorphic adenoma

    Jul 30, 2021 · Pleomorphic adenoma is a benign triphasic salivary gland neoplasm composed of epithelial (ductal) cells, myoepithelial cells and chondromyxoid stroma

  9. Adenocarcinoma of the esophagus and GE junction

    Adenocarcinoma of the esophagus and esophagogastric junction is a malignant epithelial neoplasm of the esophagus with glandular or mucinous differentiation

  10. Pathology Outlines - Small cell carcinoma

    Sep 20, 2022 · Positive for p40 and high molecular weight keratins, negative neuroendocrine markers (CD56, synaptophysin, chromogranin) Lung adenocarcinoma, poorly differentiated: Negative for …