The novel PDE10A inhibitor CPL'36 offers a new mechanism of action and is both safe and effective for acute exacerbations of schizophrenia, new research suggests.

Purpose: A rare adverse effect observed after dose escalation of topiramate therapy is discussed. A review of published cases, monitoring recommendations, and important counseling information for ...

Rheumatoid arthritis is the most common etiology for inflammatory arthritis in the older population, with an estimated prevalence of 2%. An older individual with inflammatory polyarthritis usually ...

Recently, ISMP Canada published a safety bulletin on oral dosing errors associated with LUGOL's solution (potassium iodide and iodine), also referred to as strong iodine solution. [1] The ...

The primary cicatricial alopecias are an uncommon, complex group of disorders that result in permanent destruction of the hair follicle, usually involving scalp hair alone. Prompt diagnosis and ...

Management of adverse events is a major concern of clinicians who use antipsychotic drugs. The incidence of motor side effects is dose dependent. Atypical antipsychotic drugs are less likely to ...

Clobazam is the first and only 1,5-benzodiazepine in clinical use as an anticonvulsant. Clobazam exerts it anticonvulsant effects via its selective affinity for the ω 2 site of the GABA-A ...

Harm Reduction Journal is an Open Access, peer-reviewed, online journal whose focus is prevalent patterns of psychoactive drug use, the public policies meant to control them, and the search for ...

Purpose: The pharmacology, pharmaceutics, clinical efficacy, adverse effects, cost, and dosage and administration of long-acting risperidone injection are reviewed. Summary: Risperidone is the ...

Background Noninvasive mechanical ventilation (NIV) is a front-line therapy for the management of acute respiratory failure (ARF) in the intensive care units. However, the data on factors and ...

Polymyalgia rheumatica (PMR) is a common inflammatory condition affecting elderly people and involving the girdles. [1] The mainstay of treatment is oral glucocorticoids (GC), with the recent BSR ...

Under a Republican-led budget bill, US doctors and dentists would no longer be able to count residency years toward the ...