clinicaltrialsarena21h
Pfizer and Arvinas’s HER2-breast cancer drug extends PFS in certain patients
Overall survival data was not yet mature with less than a quarter of the required number of events having occurred. Credit: Shutterstock / Maria Sbytova. Pharma giant Pfizer and Arvinas’s human ...
clinicaltrialsarena21h
J&J and Protagonist’s icotrokinra scores in Phase IIb UC study
J&J and Protagonist Therapeutics are collectively developing icotrokinra, which is poised to be an immunology blockbuster. Image credit: Emily frost / Shutterstock. Johnson & Johnson (J&J) and ...
Clinical Trials Arena1d
Amgen and Kyowa Kirin’s rocatinlimab trial for atopic dermatitis meets endpoints
Amgen and Kyowa Kirin have reported that the 24-week Phase III IGNITE trial assessing two dose strengths of rocatinlimab, in ...
Clinical Trials Arena1d
AstraZeneca reports positive outcomes from trial of Imfinzi
AstraZeneca has reported positive “high-level” outcomes from the Phase III MATTERHORN trial of Imfinzi (durvalumab) with FLOT chemotherapy.
Clinical Trials Arena1d
Merck KGaA’s lupus drug fails in SLE cohort of Phase II trial
Merck’s lupus drug enpatoran has failed to meet the primary endpoint in a subgroup of patients, but the drug's development is ...
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PDS Biotechnology commences trial for head and neck squamous cell carcinoma
The trial is structured for enrolling nearly 350 subjects. Credit: Joyseulay/Shutterstock. PDS Biotechnology has commenced the randomised, multi-centre Phase III clinical trial, VERSATILE-003, to ...
clinicaltrialsarena1d
Mineralys’s stock soars as hypertension pill scores in two pivotal trials
The Phase II and Phase III trials show the therapy is effective at dropping blood pressure. Image credit: Good dreams – Studio / Shutterstock. Mineralys Therapeutics’s oral hypertension therapy, ...
clinicaltrialsarena1d
Novo Nordisk’s stock drops despite CagriSema hitting goal of Phase III trial
The company’s stock, listed on the Copenhagen market, dropped by 9% on the news, from a DKr598 ($86.91) market open on 0 March to a DKr544 low. Credit: Shutterstock / JHVEPhoto. Novo Nordisk’s ...
clinicaltrialsarena1d
Eli Lilly’s three-year Ebglyss study leaves 50% of AD patients with clear skin
The company announced that at week 16, more than 83% of patients dosed with Ebglyss no longer required the use of concomitant therapies such as topical corticosteroids. Credit: Shutterstock / Kmpzzz.
Clinical Trials Arena4d
Persica’s antibiotic-based drug alleviates lower back pain in Phase Ib trial
Persica's antibiotic-based drug could benefit patients with chronic lower back pain who are suffering from an infection in ...
Clinical Trials Arena4d
Everest Medicines begins dosing in mRNA cancer vaccine trial
Everest Medicines has dosed the first subject with EVM16, the company’s personalised mRNA cancer vaccine, in the EVM16CX01 ...
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J&J drops Phase III MDD programme due to lack of efficacy
J&J is now looking to trial the therapy in other indications but has not specified details. Image credit: Shutterstock / josefkubes. Johnson & Johnson (J&J) is dropping its Phase III major depressive ...