Liver fibrosis should be assessed in all individuals with chronic liver disease as it predicts the risk of future liver-related morbidity and thus need for treatment, monitoring and surveillance.
Disruption of CerS6-mediated sphingolipid metabolism by FTO deficiency aggravates ulcerative colitis
1 State Key Laboratory of Systems Medicine for Cancer; Key Laboratory of Gastroenterology & Hepatology, Ministry of Health; Division of Gastroenterology and Hepatology; Shanghai Cancer Institute; ...
Background Intestinal fibrosis is a common complication of inflammatory bowel disease, and its core pathogenesis is fibroblast activation and massive extracellular matrix (ECM) deposition. In recent ...
Dr L Lundell, Department of Surgery, Sahlgrenska University Hospital, S-413 45 Göteborg, Sweden. BACKGROUND Endoscopic oesophageal changes are diagnostically helpful and identify patients exposed to ...
Objective In the tumour microenvironment, critical drivers of immune escape include the oncogenic activity of the tumour cell-intrinsic osteopontin (OPN), the expression of programmed death ligand 1 ...
Professor J P Galmiche, Centre de Recherche en Nutrition Humaine, CRI INSERM 95-08, CHU, Hôtel Dieu, Place A Ricordeau, 44035 Nantes cedex 01, France. Email:galmiche{at}easynet.fr BACKGROUND/AIM ...
Objective Hepatitis D virus (HDV) is a defective virus that completes its life cycle only with hepatitis B virus (HBV). The HBV with HDV super-infection has been considered as one of the most severe ...
Department of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, Arizona, USA Correspondence to: Dr K Dvorak Department of Cell Biology and Anatomy, PO Box 245044, ...
BACKGROUND/AIMS Intestinal metaplasia (IM) is a common finding at the oesophagogastric junction, but the aetiopathogenesis of the different IM subtypes—that is, incomplete IM (specialised columnar ...
4 Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Belgium Correspondence to Dr Marc Ferrante, Department of Gastroenterology and Hepatology, University Hospitals ...
Correspondence to Dr Jonathan D Schertzer, McMaster University Faculty of Health Sciences, Hamilton, ON L8S 4K1, Canada; schertze{at}mcmaster.ca Microbiota are a source of low-grade inflammation ...
Background Microbiota-host interactions are crucial in the progression of inflammatory bowel disease (IBD). Despite extensive research, the detailed mechanisms through which these interactions ...
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