This article was originally published on www.si.com/nfl/jaguars as Jaguars Must Solve 49ers Defense to Stay Competitive in ...

The Jacksonville Jaguars have gotten two impressive wins in the first three weeks of the 2025 NFL season, but the world isn't ready to crown them just yet. Much ...

Awaiting the Jacksonville Jaguars in Week 4 is a road matchup with the San Francisco 49ers. This game is expected to be the ...

The Jacksonville Jaguars play the San Francisco 49ers in Week 4 of the 2025 NFL season. Who wins? See our predictions and picks, plus the game odds.

Get the best Jaguars vs. 49ers predictions ahead of Sunday's clash at Levi's Stadium. Free NFL picks for September 28.

The Jacksonville Jaguars have one of the toughest tests in the early portion of the regular season when they take on the undefeated San Francisco 49ers in Santa ...

San Francisco 49ers tight end George Kittle talked about all things Grateful Dead with Barstool Sports' Big Cat on his new podcast.

The 3-0 San Francisco 49ers host the 2-1 Jacksonville Jaguars on Sunday. The 49ers are red hot despite all the adversity they faced in the first few weeks of football.

The San Francisco 49ers take on the AFC South’s Jacksonville Jaguars at Levi’s Stadium on Sunday, Sept. 28 at 1:05 p.m. PDT.

Defensive coordinator Robert Saleh of the San Francisco 49ers talks with Fred Warner during the game against the Seahawks at ...

San Francisco 49ers coach Kyle Shanahan revealed that star edge rusher Nick Bosa underwent successful ACL surgery after a ...

San Francisco 49ers head coach Kyle Shanahan shared the results of edge rusher Nick Bosa's knee surgery on Friday.