The Buffalo Bills were short on defense due to injuries, but one of their Day 3 draft selections stepped up and was named among the NFL’s biggest winners

The Bills will wear all-white uniforms in a “white out” against the Patriots on SNF, as Highmark Stadium turns into a blizzard of support.

High expectations have their price, leaving Josh Allen and the Buffalo Bills unhappy, but relieved, following a close call against the winless New Orleans Saints

Buffalo is looking to put an absolute stranglehold on the AFC East through five weeks. At 4-0 they are two games ahead of the Patriots in the divisional standings. The Dolphins and Jets have just one combined win at the bottom of the division.

Buffalo is a 14.5-point favorite in the latest Saints vs. Bills odds from SportsLine consensus, while the over/under for total points scored is 48. The Bills are -1562 money line favorites (risk $1,562 to win $100),

Two more games remain on Monday night, but the odds are out for Week 5, and it’s time to do some early prognosticating.

Six NFL teams entered Week 4 undefeated but only two remain. And they're the Super Bowl favorites. The Buffalo Bills and Philadelphia Eagles are the only 4-0 teams left in the league.

With a two-game lead in the AFC East, the AI PickBot is expecting a knockout punch by the Bills and rates their cover as an A+ pick and also predicts a 34-19 win on average. See its other Week 5 football predictions and football picks at SportsLine.