Christian Pulisic will not feature for AC Milan in their crucial Serie A clash against Juventus due to injury, head coach Sérgio Conceição confirmed on Friday.

Domestic league action is back this weekend with Arsenal vs. Aston Villa, Juventus vs. Milan and Manchester United vs. Brighton and Hove Albion all notable on top of the U.S. men's national team taking on Venezuela.

There are renewed injury concerns for Christian Pulisic after the United States international limped out of AC Milan's match at Como.

The 26-year-old Pulisic went down after being caught on the ankle by Como defender Marc-Oliver Kempf. He immediately waved the medical staff over and appeared to be pointing to his left thigh.

USMNT winger Christian Pulisic is facing another injury after he was replaced by AC Milan manager Sergio Conceicao only a few minutes before halftime on Tuesday during the Rossoneri's match against Como.

This weekend’s clash between Juventus and AC Milan feels like a must-win for both sides. Two of Italy’s traditional powerhouses find themselves under pressure, and their hopes of achieving season goals may hinge on this match.