Penn Engineers have redesigned a key component of lipid nanoparticles (LNPs), the delivery vehicles behind mRNA vaccines, to steer the particles toward lymph nodes while reducing off-target delivery ...

Performance of circulating tumor DNA as a biomarker in testicular seminoma and non-seminomatous germ cell tumor patients undergoing primary retroperitoneal lymph node dissection. Test statistics for ...

Contemporary survival and treatment outcomes in malignant spermatic-cord tumors: A two-decade population-based analysis. This is an ASCO Meeting Abstract from the 2026 ASCO Genitourinary Cancers ...

This illustration depicts a newly identified pathway, an intranodal lympho-venous shunt, within a lymph node that enables lymph fluid to flow directly into a blood vessel. Typically, lymph nodes serve ...

Mouse research shows tattoo pigments move into lymph nodes within minutes and persist for months Ink triggered immune-cell death, chronic inflammation and weakened response to an mRNA COVID shot ...

Scientists have found that preserving lymph nodes during cancer surgery could dramatically improve how patients respond to immunotherapy. The research shows that lymph nodes are essential for training ...

Limited data are available on survival outcomes after sentinel-lymph-node biopsy alone as compared with lymphadenectomy in cervical cancer. In this multicenter, randomized, noninferiority trial, we ...

Removing lymph nodes during cancer surgery has saved countless lives in many tumour types. Yet recent research is challenging parts of this long-standing practice. Imagine your body’s immune defences ...

As an oncologist, I’m often asked by family and friends about swollen lymph nodes. Even I find them concerning at times, wondering if they could be a sign of cancer. I should know better. Most lymph ...

"Our research suggests that removing lymph nodes during cancer surgery, a common practice to prevent tumour spread, may inadvertently reduce the effectiveness of treatments, such as checkpoint ...

A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role ...

Papillary thyroid cancer (PTC) generally has a good prognosis, with 5-year relative survival rates of 99% for regional cancer that has spread to the lymph nodes. PTC is the most common type of thyroid ...