Specific FBN1 variants are associated with an increased risk for severe mitral regurgitation and surgery in Marfan syndrome.

Background Marfan syndrome (MFS) is a multisystemic disorder caused by pathogenic (P) variants in the fibrillin-1 gene (FBN1), associated with life-threatening cardiovascular complications. Early ...

Wes Streeting set to hail result as proof of progress, but Britons remain frustrated with long waits for GP hospital care Public satisfaction with the NHS has risen for the first time since 2019, but ...

What is iliotibial band syndrome? Iliotibial band syndrome (often called “IT band syndrome”) is a medical condition that causes pain on the outside of the knee. It most commonly happens in athletes, ...

Five NHS trusts with "deep-rooted challenges" will be the first to be placed in a new recovery programme, the health secretary has announced. Wes Streeting said "failure has been tolerated for too ...

Two hospital trusts in East Yorkshire and Lincolnshire have been included in an NHS plan to tackle the "worst services in the country", the health secretary has announced. Hull University Teaching ...

Only one-in-five people under 35 say they are satisfied with the NHS compared with more than a third of people aged 65 and over, an analysis of the annual British social attitudes survey shows.

The 10 Year Health Plan sets out an ambition to build a truly modern NHS that delivers better treatment for patients and better value for taxpayers. To realise this vision, we must deliver services in ...

“Ryan was my life. Every day when you wake up, you forget for a split second. Then it hits. Then you walk by his bedroom, and he’s not there.” Four years on, Sarah Rowantree still questions what ...