San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL ...

Yet another San Francisco 49ers running back seems set to miss some action, as ESPN insider Adam Schefter reports “it looks as if” Isaac Guerendo will miss Sunday’s matchup against the Miami ...

Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...

Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The ...

There are numerous player prop betting options on Isaac Guerendo for the 8:15 PM ET game Monday, which airs live on ABC/ESPN.

That was until Isaac Guerendo showed up. The rookie fourth-round pick in 2024 stepped into action on Sunday in Week 14, dominating the Bears to the tune of 128 total yards and two touchdowns.

Guerendo (foot) is listed as active Thursday against the Rams, Lindsey Pallares of the 49ers' official site reports. Guerendo came out of this past Sunday's win versus the Bears with a sprained ...

And what we’ve got with Isaac Guerendo is some risk. The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” and ...

The latest injury update for San Francisco 49ers running back Isaac Guerendo in Week 15 against the Los Angeles Rams. San Francisco 49ers running back Isaac Guerendo. / Bob Kupbens-Imagn Images ...

San Francisco 49ers running back Isaac Guerendo is dealing with a hamstring injury and is unlikely to play Sunday at the Miami Dolphins, a source told ESPN's Adam Schefter on Thursday. Guerendo ...

Curious to know about 49ers RB Isaac Guerendo‘s injury? The standout rookie has drawn attention for his breakout performances on the field and his determination to play despite a recent foot injury.

San Francisco 49ers running back Isaac Guerendo is active on Thursday night against the Los Angeles Rams despite his sprained foot. Guerendo, who was listed as questionable, insists he "feels good ...