ESPN’s Adam Schefter reported that San Francisco 49ers running back Isaac Guerendo will try to play tonight against the Los ...

The rookie running back did not practice last week and has been officially ruled out of Sunday’s clash at Hard Rock stadium ...

The 49ers went after Guerendo in the draft because he reminded them a lot of Mostert, whom they'll face Sunday in Miami.

The San Francisco 49ers are banking on rookie running Isaac Guerendo to fill the shoes left by a former Offensive Player of ...

As the first quarter wound down in his second NFL game, San Francisco 49ers running back Isaac Guerendo trotted ... No. 129 overall -- on Guerendo in April's NFL draft. The idea was to add the ...

Christian McCaffrey and Jordan Mason are both injured, so Guerendo is set for his chance as San Francisco’s starting running ...

Should Guerendo start as expected Sunday, it will be just his second start as a running back since he was in the fourth grade ...

San Francisco 49ers rookie Isaac Guerendo didn't transition to playing ... who selected him in the fourth round of the NFL Draft. Injuries have ravaged the 49ers' roster this season, and the ...

Curious to know about 49ers RB Isaac Guerendo‘s injury? The standout rookie has drawn attention for his breakout performances ...

San Francisco 49ers running back Isaac Guerendo plans to play Thursday night against the Los Angeles Rams despite his ...