The San Francisco 49ers likely will be without rookie running back Isaac Guerendo for Sunday’s game against the Miami Dolphins.

San Francisco 49ers running back Isaac Guerendo has been diagnosed with a sprained foot, head coach Kyle Shanahan announced on Monday. Ian Rapoport @RapSheet <a href ...

Isaac Guerendo had to exit Sunday’s win over the Bears with a foot injury. While the club called him questionable to return, there was no reason to put him back in the game with San Francisco up by a ...

With both McCaffrey and Jordan Mason on injured reserve as the 49ers head down the stretch, they turned to rookie Isaac Guerendo with some Patrick Taylor Jr. thrown in for good measure and it was ...

Coach Kyle Shanahan said after Sunday's 38-13 win over the Bears that Guerendo possibly has a foot sprain, Eric Branch of the San Francisco Chronicle reports. Guerendo exited in the fourth quarter ...

San Francisco 49ers rookie running back Isaac Guerendo sustained a foot injury and was questionable to return in Sunday's matchup with the Chicago Bears. More News: Chargers Make Game-Time ...

Guerendo (foot) is questionable to return to Sunday's game against the Bears. He rushed 15 times for 78 yards and two touchdowns while catching both of his targets for 50 yards prior to the injury ...

The San Francisco 49ers may be down to their fourth-string RB after Isaac Guerendo suffered a foot injury against the Chicago Bears. San Francisco beat Chicago 38-13 in what may have been the best ...

Running back Isaac Guerendo went to the locker room in the fourth quarter with a foot injury. The team calls him questionable to return, but it's a safe bet that his day is done with the 49ers up ...