A 112-fold increase in multiply-spliced HIV RNA (Tat-Rev transcripts) HIV transcription exceeded that triggered by standard mitogens (PMA/PHA) And a 17.2-fold increase in HIV virion production in ...

About Virion Therapeutics (Virion) Virion Therapeutics, LLC is a clinical-stage company developing novel T cell-based immunotherapies to cure cancer and chronic infectious diseases that utilize ...

Env trimers have been engineered to mimic the native structure of the HIV Env on the surface of the HIV virion,” shared first author Dr. William Hahn, a Clinical Assistant Professor at the University ...

We can see the entire-- All the explosive events that occurred during HIV virion assembly. And, really, we're visualizing the central dogma. We're seeing RNAs being made.

A patient with a 33-year history of HIV-1 infection who underwent stem-cell transplantation for the treatment of acute myelogenous leukemia remained HIV-1 free nearly 5 years later.

Susan P Buchbinder and colleagues1 express concern that COVID-19 vaccines utilising replication-defective adenovirus vectors of human serotype 5 (HAdV-5) might increase the risk of HIV-1 acquisition.

A large number of human immunodeficiency virus 1 (HIV-1) integrase (IN) alterations, referred to as class II substitutions, exhibit pleiotropic effects during virus replication. However, the ...

The virion can “survive” in the environment for a certain period of time, ... Cats have the feline immunodeficiency virus or FIV, a cat version of HIV, which causes AIDS in humans.

Effect of CCL2 on HIV-1 replication is mediated by mobilization of ALIX from F-actin leading to enhanced virion release and improved fitness and this requires the Gag late motif, LYPX.

LONDON--(BUSINESS WIRE)--Virion Biotherapeutics announced today the appointments of Vanessa King, PhD, as President & Chief Executive Officer and Isabel Najera, PhD, as Chief Scientific Officer.

The negative effect of EZ-TD on HIV-1 virion production is predominant to the positive effect on HIV-1 entry. Taken together, our results indicate that ezrin is involved in many steps of the HIV-1 ...

This prevented the immature HIV virion particle from properly developing into an infectious and mature HIV viral particle. Figure 4: Maturation Inhibitor Bevirimat and its Mode of Action.