BMJ

#7178 Case Study: uncommon clinical presentation of auto immune encephalitis in an adolescent female

1 MBBCh (Wits), MMed (Wits), FCPsych (SA), FCNeuropsych South Africa Definitive management for autoimmune encephalitis includes first-line immunotherapy (corticosteroids, intravenous immunoglobulins, ...
Yale Environment 360

SARS-CoV-2 is on the decline in animals, study finds

During the first few years of the COVID-19 pandemic, the virus SARS-CoV-2 was detected in an increasing number of non-human animal species. This included many wild animal species as well as domestic ...
eLife

The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective

A major health challenge resulting from the COVID-19 pandemic is the manifestation of post-acute sequelae of SARS-CoV-2 (PASC). PASC (or long COVID) is a collective term used for clinical symptoms, ...
C&EN

Reprogramming the SARS-CoV-1 Neutralizing Antibody S230 to SARS-CoV-2 via Directed Evolution and Molecular Docking-Based Binding Mode Analysis

Department of Biomedical Sciences, Graduate School, Korea University, Seoul 02707, Republic of Korea BK21 Graduate Program, Department of Biomedical Sciences, Korea University College of Medicine, ...
The Lancet

Targeting the SARS-CoV-2 reservoir in long COVID

bDepartment of Infectious Diseases and Unit of Post-COVID Huddinge, Karolinska University Hospital, Stockholm, Sweden cDepartment of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden ...
PNAS

Spike destabilization attenuates Mink Cluster 5 SARS-CoV-2

Spillover and subsequent evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in nonhuman hosts is not well understood. The largest cases of this have occurred in farmed mink, ...
Kaleido Scope

SARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds

A multi-institutional study led by researchers at the University of Alabama at Birmingham and the University of North Carolina at Chapel Hill has revealed a previously underappreciated mechanism by ...
GEN

Host Proteins Identified in SARS-CoV-2 Replication Pathways Reveal Drug Targets

The global pandemic may be over, but SARS-CoV-2 continues to infect people around the world. Indeed, the United States has recorded roughly 750 deaths from COVID-19 over the past month. Now, an siRNA ...
PNAS

Broad neutralizing antibody response of a monomeric spike–based SARS-CoV-2 bivalent vaccine against diverse variants

This study analyzed the immunological mechanisms underlying the elicitation of broadly neutralizing antibodies (bnAbs) by a severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) bivalent vaccine ...
Medscape

SARS-CoV-2 Infection Tied to Early Vascular Aging

SARS-CoV-2 infection is linked with early vascular aging in the long term, especially in women, according to a recent study in the European Heart Journal. In the multicenter CARTESIAN study, ...
Kaleido Scope

Groundbreaking research uncovers link between SARS-CoV-2 and lung foam cell formation

Approximately 15 to 20 million Americans who have acquired COVID-19 experience persistent symptoms lasting over 3 months (long-COVID). Respiratory symptoms of long-COVID include breathlessness, ...