Abstract: Accurate detection of the human metaphase chromosome centromere is an important step in many chromosome analysis and medical diagnosis algorithms. The centromere location can be utilized to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. To obtain further insight into the roles of ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Homologous recombination is a largely ...

Abstract: To evaluate the function of cohesin and its regulators, classifications of chromosomes based on the positional relationship between sister chromatids are used. Although the analysis has been ...

Human chromosomes (human normal karyotype). Humans have 23 pairs of chromosomes, with one set inherited from each parent. The main difference between the karyotype of a female and a male lies in the ...

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural ...

In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture ...