Scientists invented a new experimental system to study how age-related changes in egg cells make them more prone to ...

Using advanced 3D live imaging, they tracked chromosome movements in real-time and observed aging-like segregation errors, including chromatid splitting events that lead to aneuploidy.

Royalty-free licenses let you pay once to use copyrighted images and video clips in personal and commercial projects on an ongoing basis without requiring additional payments each time you use that ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Homologous recombination is a largely ...

Rationale: A cell has DNA strands of different replication ages because DNA replication is semi-conservative. Double-stranded DNA molecules possess one DNA strand that is one generation older than the ...

Our studies aim at getting a basic understanding of how cells shape and segregate their genetic material that can be applied on genome integrity and development concerns. A prerequisite for maintained ...

Human chromosomes (human normal karyotype). Humans have 23 pairs of chromosomes, with one set inherited from each parent. The main difference between the karyotype of a female and a male lies in the ...

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with ...

Tokyo, Japan – Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural ...

In early cytological studies chromatids of metaphase chromosomes were suggested to coil into a spiral called chromonema. This assumption was recently supported by chromosomce conformation capture ...

While technological advances in radiation oncology have led to a more precise delivery of radiation dose and a decreased risk of side effects, there is still a need to better understand the mechanisms ...