The San Francisco 49ers are headed to the 2025 offseason as they look to retool their coaching staff and roster after a ...

The 49ers were already out of playoff contention, and the Lions had little to play for, but that didn’t stop fans from tuning in on Monday night. Lions-49ers was the most-watched Monday Night Football ...

Tensions were high in the first quarter of a Monday night game between the Detroit Lions and the San Francisco 49ers. The Lions were looking for one more win to build momentum ahead of an NFC ...

Jared Goff threw three touchdown passes and the Detroit Lions tuned up for their Week 18 division showdown against Minnesota by beating the San Francisco 49ers 40-34 on Monday night. Goff threw a ...

Brock Purdy threw for a career-high 377 yards and three touchdowns as the San Francisco 49ers fell to the Detroit Lions 40-34 at Levi's Stadium on Monday Night Football. Purdy also threw two ...

The Detroit Lions technically didn’t need to win Monday night’s matchup with the San Francisco 49ers, begging the question of whether head coach Dan Campbell would pull his starters at some ...

Santa Clara, Calif. — The Detroit Lions' primetime matchup against the San Francisco 49ers on Monday night doesn't have the significance many believed it would at the time of scheduling.

After his second interception against the San Francisco 49ers on Monday night, Detroit Lions safety Kerby Joseph revived a former 49ers star's famed celebration. Joseph picked off Brock Purdy ...

With last place in the NFC West clinched, the 49ers know exactly which teams they will face during the 2025 NFL season. The order in which they face them, however, remains to be seen. San ...

The San Francisco 49ers' disappointing season continued on "Monday Night Football" against the Detroit Lions. At first, things looked good for the 49ers as they took a 21-13 lead into halftime.