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Post-implantation embryo models built entirely from human stem cells.
In addition to revealing these antimicrobial properties of keratinocytes, the model helped the scientists identify tuft cells, a type of cell not previously known to be in the conjunctiva.
Establishing human cell models of spinal muscular atrophy (SMA) to mimic motor neuron-specific phenotypes holds the key to understanding the pathogenesis of this devastating disease.