A novel compound that inhibits the BAF chromatin remodeling complex causes regression in an animal model of the incurable cancer uveal melanoma.

ChemMatters, ACS's award-winning high school chemistry magazine, helps high school students make connections between chemistry and the world around them. ChemEd X, published under the ACS Division of ...

Aficamten is also currently being evaluated in ACACIA-HCM, a Phase 3 clinical trial of aficamten in patients with non-obstructive HCM; CEDAR-HCM, a clinical trial of aficamten in a pediatric ...

Present day synthesis produces unimaginable levels of organic solvent waste; chemo- and biocatalysis in water are solutions to this problem. Learn how to utilize combinations of chemo- and ...

BACKGROUND: PYGM (muscle glycogen phosphorylase), the rate-limiting enzyme in glycogenolysis, plays an indispensable role in maintaining cardiac energy metabolism. However, the role of PYGM in the ...