The Detroit Lions visit the San Francisco 49ers on Monday at 8:15 p.m. ET, in a matchup featuring two of the best offensive ...

The San Francisco 49ers released a statement on the passing of Trent Williams’ son. “The 49ers mourn the passing of Trent Williams' son and send him and his family all our love,” the 49ers ...

Though, more and more you could make an argument the most dangerous job is that of running back for the San Francisco 49ers. The damage rate is incredible. Rewind back to Week 1 of the season.

The San Francisco 49ers aim to improve their 5-7 record in Week 14 when they take on the Chicago Bears. However, injury woes have plagued the roster, with the regular season approaching an end.

On the heels of a third consecutive defeat, the 49ers' place in the 2025 NFL Draft is as important as their rapidly fading spot in the NFC playoff picture. Following San Francisco's 35-10 loss to ...

San Francisco 49ers star Christian McCaffrey will not play the rest of the 2024 season. Kyle Shanahan said that Christian McCaffrey did injure his PCL and it is a 6-week recovery. His season now ...

San Francisco 49ers player Trent Williams and his wife Sondra are mourning the passing of their newborn son, the couple revealed on Monday. "It's been extremely hard trying to process the saddest ...

49ers left tackle Trent Williams’ wife Sondra announced the tragic death of their newborn son, Trent Jr. In a post on Instagram on Sunday, Sondra revealed that she lost Trent Jr.’s twin early ...

Orchard Park, N.Y. — The Buffalo Bills dominated the San Francisco 49ers on a snowy night at Highmark Stadium, winning 35-10 and clinching the AFC East title for the fifth consecutive season.

and past the 49ers, 35-10, in a game that saw and Josh ... youngsters Nakobe Dean and Reed Blankenship have made the leap, and free agent addition Zack Baun is a star. Credit Howie Roseman ...

The San Francisco 49ers are in dire straights after a blowout loss to the Buffalo Bills, and QB Brock Purdy knows it. San Francisco dropped to 5-7 after a 35-10 defeat in Buffalo. After the major ...

Check out these NFL Week 14 picks and NFL Week 14 predictions for the game, which can be seen at 2:25 p.m. MST on FOX (stream with free trial from FUBO). The 49ers are a 4-point favorite over ...