Over the last several seasons, the Los Angeles Rams and San Francisco 49ers have battled for first place in the NFC West, with both teams winning it twice in the last four years. The 49ers are sitting in first place in the West for the moment as these two are set to square off in their first

What’s at stake, injuries, key matchup to watch, TV info, fantasy sleeper and prediction for Thursday night’s game between the NFC West rivals.

The San Francisco 49ers head into Thursday Night Football against the Los Angeles Rams, with a 3-1 record, matching their division rivals. It’s a big early-season matchup, and the 49ers aren’t hiding anything,

In the studio: TNF studio presence Andrew Whitworth blocked for Stafford in the Rams’ 2021 Super Bowl campaign. Fellow analyst Richard Sherman was born in Compton, went to Stanford and played for the 49ers. A third member of the team, Tony Gonzalez, hails from Torrance (southwestern Los Angeles County).

Brock Purdy will miss the 49ers' "Thursday Night Football" game against the Rams after his toe injury flared up, and Mac Jones will make his third start.

WOODLAND HILLS, Ca. The Los Angeles Rams have been working around the clock to prepare for their Thursday Night matchup against their arch-rivals, the San Franc

For the first time since October 2022, the 49ers are underdogs against the Los Angeles Rams. The line initially opened with Sean McVay’s squad as 3.5-point favorites. Then, the injury news surfaced for the 49ers,