Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Losses by South Florida and Memphis cleared out two playoff contenders and improved the Aztecs’ chances for an improbable run ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

San Diego scores twice during the final eight minutes to beat Oregon State and win the conference championship.

The San Francisco 49ers (6-4) visit the Arizona Cardinals (3-6) Sunday in Week 11. Kickoff from State Farm Stadium in ...

The Spurs, missing Victor Wembanyama and with Stephon Castle available for only a half, snapped a two-game losing streak by ...

Texas Tech beat BYU, Houston and Utah but lost to Arizona State. BYU beat Utah, and Utah beat Cincinnati. Houston and Utah ...

Police were called about 12:25 a.m. to the 3000 block of 16th Street on reports of a shooting. SAN FRANCISCO - A 23-year-old ...

Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and ...

The recent blowback to Salesforce's CEO shows the challenges corporate leaders face as they wrestle with political and cultural collisions.

Law enforcement is urging drivers to stay vigilant and practice safe driving due to wet weather creating slippery conditions ...