Here are the top five PrizePicks plays for Week 5 of Thursday Night Football, featuring a matchup between the 49ers and Rams.

The Rams shut down Saquon Barkley. They neutralized Jonathan Taylor. Now here comes Christian McCaffrey. On Thursday night, the Rams’ defense gets another opportunity to prove it should be regarded ...

The Los Angeles Rams will play host to the San Francisco 49ers Thursday night at SoFi Stadium. Three-teams are in a tie for first in the NFC West, and Rams quarterback Matthew Stafford and 49ers ...

Here's everything you need to know about the Rams vs. 49ers, including TV channel and live stream options for the game. Rams vs. 49ers will not air on a national TV channel. Viewers can stream the ...

Week 5 of the NFL kicks off with a high-voltage divisional matchup between the 49ers and the Rams, two 3-1 teams looking to establish themselves as leaders in the NFC West. The gam ...

Fred Warner has embodied the San Francisco 49ers and their hard-hitting defensive style to Puka Nacua for the Rams receiver’s entire adult life. That’s because Nacua was still in high school when he ...

The San Francisco 49ers visit the LA Rams in a marquee divisional matchup on Thursday Night Football at SoFi Stadium in Inglewood, California.

In his first full game as a 49er against the Rams, McCaffrey had a rushing touchdown, a receiving touchdown and even threw a touchdown pass.

San Francisco 49ers head coach Kyle Shanahan held a press conference with reporters on Tuesday, prior to the team's showdown with the Los Angeles Rams on Thursday Night Football. Given the short ...

Matthew Stafford and the Los Angeles Rams will take on the San Francisco 49ers at SoFi Stadium on Prime Video on Thursday, October 2, 2025. Prop wagers open at 21 pass completions, 33 passing attempts ...

J.B. Long breaks down the Los Angeles Rams’ recent run game efficiency, examines the challenges running back Christian McCafffrey poses in the passing attack, and highlights wide receiver Puka Nacua’s ...

Tomorrow begins the battle for the NFC West title as the Los Angeles Rams and San Francisco 49ers will tango at SoFi Stadium on Thursday night. This is the Rams ...