The San Francisco 49ers could potentially be without even more key pieces when they take on the Jacksonville Jaguars on Sunday.

Defensive coordinator Robert Saleh of the San Francisco 49ers talks with Fred Warner during the game against the Seahawks at ...

The San Francisco 49ers could target a top Miami Dolphins defender in a trade to help replace injured Nick Bosa.

The San Francisco 49ers are reportedly keeping a close eye on a teammate of Tua Tagovailoa on the Miami Dolphins to aid key absences like Nick Bosa and Brock Purdy’s.

A first-round pick of the Dolphins in 2021, the 26-year-old logged 8.5 sacks as a rookie and followed that up with seven sacks in 2022. He appeared on track for a career year in 2023, with 6.5 sacks ...

The Dolphins have also had two players not practice all week: cornerbacks Storm Duck (ankle) and Jason Marshall Jr.

The 49ers face challenges after Nick Bosa's injury. Would a Bradley Chubb trade be the solution to bolster their defense?

Former Colorado Buffaloes safety Shilo Sanders' NFL career may not be over yet after he worked out with the San Francisco 49ers on Tuesday.

The San Francisco 49ers have not been afraid to make big in-season trades during John Lynch's tenure as their General Manager. That's a good thing considering the defense's need for a talent infusion ...

Miami Dolphins head coach Mike McDaniel was the offensive coordinator for the San Francisco 49ers from 2017-2022 under Kyle ...

Two teams have played the Super Bowl in their home stadium, and a third — the 49ers — played in its home region.