This year’s MVP frontrunner could put up some big numbers against one of the NFL’s worst teams in Week 4. Josh Allen and the ...

Buffalo has improved to a 3-0 start to the 2025 season, and Cook has had 284 yards, four touchdowns, and nine catches for 71 ...

After a disappointing showing in Seattle, the New Orleans Saints’ defense will look for a rebound performance when they face ...

According to FanDuel, the Buffalo Bills (-10000) have the best odds for a playoff berth, followed by the Baltimore Ravens ...

Get a prediction, pick and odds for the NFL Week 4 matchup between the Buffalo Bills and the New Orleans Saints.

We searched high and low for a brave soul who picked the New Orleans Saints to beat the Buffalo Bills on Sunday.

This isn't the week for Spencer Rattler to throw 40 times, but the Saints passing offense must still make plays. Breaking down their Bills matchup: ...

Get the best Saints vs. Bills predictions ahead of Sunday's showdown in Buffalo. Free NFL picks for September 28.

USA Today's NFL experts make their picks for a Week 4 showdown between the Buffalo Bills and New Orleans Saints ...

NFL Week 4 odds, picks, predictions, TV channel, streaming information for the Sunday football game between the New Orleans Saints and Buffalo Bills.

Bills rookie Jackson Hawes has a 91.8 PFF grade, the highest of any tight end in the NFL. He’s also the league’s top-graded rookie after three weeks.

New Orleans Saints head coach Kellen Moore speak with the media from the Ochsner Sports Performance Center on Friday, September 26, 2025 ahead of Week 4 vs. the Buffalo Bills.