Buffalo is a 14.5-point favorite in the latest Saints vs. Bills odds from SportsLine consensus, while the over/under for total points scored is 48.5. The Bills are -1493 money line favorites (risk $1,

The Buffalo Bills were short on defense due to injuries, but one of their Day 3 draft selections stepped up and was named among the NFL’s biggest winners

Two more games remain on Monday night, but the odds are out for Week 5, and it’s time to do some early prognosticating.

We grabbed the Saints +2.5 hosting the Giants early Monday before the worst was confirmed, figuring that while the Giants deserved an upgrade in the ratings from last week due to the QB switch, they had to be marked down enough with the Nabers injury that the Saints should probably be favored.

“It seems like he's getting better each and every week, which is hard to imagine," Allen said of Cook. "The way that he has this patient to hit the hole, but when he hits it, he is shot out of a cannon. His contact balance is unbelievable, his jump cuts are awesome. I'm glad he's on our team.”

Six NFL teams entered Week 4 undefeated but only two remain. And they're the Super Bowl favorites. The Buffalo Bills and Philadelphia Eagles are the only 4-0 teams left in the league.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 39-19 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

Another NFL Sunday has arrived, and two of the six undefeated teams will go head-to-head in Week 4. Here are all the highlights from Sunday's games!