Carolina is coming off a huge emotional win over Atlanta, but a much tougher opponent is lurking next on the schedule.

SANTA CLARA, Calif. (AP) — Brock Purdy returned to the lineup and the San Francisco 49ers scored their most points in nearly two years. While Purdy looked sharp in the 41-22 victory over the Arizona Cardinals on Sunday, the reasons behind the big scoring output have to do with a lot more than just the change at quarterback.

Christian McCaffrey National Football League San Francisco 49ers Top Plays NFL - San Francisco 49ers vs. Arizona Cardinals - 11/16/2025

The 49ers drafted Martin to play their WILL spot, which is the weakside linebacker spot. This is the position Dee Winters plays, not Warner and Bethune. Warner played the MIKE, which is in the middle, and gets the defense aligned. The WILL is more about run-and-chase. They are asked to do different things.

The San Francisco 49ers brought in Asante Samuel Jr. for a workout on Monday, evaluating the veteran cornerback as he works his way back into the NFL after undergoing spinal fusion surgery during the offseason. Samuel had visited several teams in recent weeks, and on Tuesday,...

George Kittle called the 49ers’ now-healthy attack “very lethal” after Brock Purdy’s impressive injury return.

Nov 16, 2025; Glendale, Arizona, USA; San Francisco 49ers quarterback Brock Purdy (13) throws the ball while Arizona Cardinals defensive lineman Walter Nolen III (97) defends in the first half at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images / Matt Kartozian-Imagn Images