When you have a mild headache or muscle ache, an over-the-counter pain reliever is usually enough to make you feel better. But if your pain is more severe, your doctor might recommend something ...

A class of synthetic drugs called nitazines have been around since the 1950s — but are quickly gaining a foothold in street drugs.

In a first, scientists used cryo-electron microscopy to visualize how opioids and the antidote naloxone (Narcan) engage the mu-opioid receptor, offering insight that could lead to better pain ...

LA County health officials are inspecting gas stations and smoke shops for kratom and more potent synthetic versions that are ...

By last winter, medetomidine was showing up in 70% of illicit opioid samples tested in Philly, along with other unregulated substances and synthetic opioids like fentanyl.

The chemical, known as 7‑OH, is found in some products marketed as kratom. While kratom itself is legal, 7‑OH can have ...

Dominic Cipriano couldn't stop shaking. A drug dealer on the streets of Kensington had sold him a bag of what he thought was ...