Owl Therapeutics ("Owl"), a biopharmaceutical company developing drugs to supercharge microglia, the immune cells of the ...

Mutations in NPC1 cause Niemann-Pick Type C. Mice lacking NPC1 only in microglia have rampant neuroinflammation and impaired ...

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's ...

Genetic differences that contribute to how long a person will live and their risk of Alzheimer's disease have been identified ...

Microglia can partially break down amyloid plaques by "spitting" a digestive enzyme at them, a new study has found.

Microglia have been revealed to first help spread Alzheimer’s disease pathology across the brain and then activate to limit ...

This study describes a valuable new model for in vivo manipulation of microglia, exploring how mutations in the Adar1 gene within microglia contribute to Aicardi-Goutières Syndome. The methodology is ...

A sequence of stress signals among specialized clean-up cells in the brain could at last reveal why some immune responses can ...

Discover how stressed-out immune cells in the brain may be the key culprit behind the development of Alzheimer's disease.

Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to ...