San Francisco 49ers WR Ricky Pearsall goes for a one-handed catch, hauling in a 31-yard pass from QB Brock Purdy.

Jacksonville Jaguar linebacker Devin Lloyd sneaks up behind San Francisco 49ers running back Christian McCaffrey and reels in an interception.

San Francisco 49ers wide receiver Ricky Pearsall catches a 32-yard ball from quarterback Brock Purdy in mid-air with one hand ...

The Jaguars took advantage of a turnover to take the lead over the 49ers early in the second quarter. On first-and-10 from ...

Jake Tonges was shaken up during the 49ers' first offensive drive and headed to the locker room for evaluation. The team ...

Brock Purdy returns to the field after a two-week absence and he’ll have Ricky Pearsall Jr. and Jauan Jennings (who were ...

San Francisco 49ers quarterback Brock Purdy admitted Christian McCaffrey and Nick Bosa have the craziest and most unique pregame rituals.

Take a look at players who have been ruled out for the San Francisco 49ers Week 4 matchup versus the Jacksonville Jaguars.

The 49ers will be waiting on Brandon Aiyuk at wide receiver, but Jauan Jennings, Ricky Pearsall Jr. and Demarcus Robinson are ...

The big question heading into today’s game for the San Francisco 49ers against the Jacksonville Jaguars wasn’t on the ...

NFL+ and NFL+ Premium allow fans access to the most NFL content available online. From game replays, coaches’ film and all-22 ...

Get the best Jaguars vs. 49ers predictions ahead of Sunday's clash at Levi's Stadium. Free NFL picks for September 28.