Celebrity attorney Alex Spiro won’t defend Mayor Eric Adams against sexual assault allegations because he’s also defending the embattled mayor against recent federal corruption charges.

Spiro is a lawyer who defies easy categorization, with a clientele as varied as it is prestigious, ranging from rap artists and sports stars to entrepreneurs and corporate giants. But the phrase ...

Mr. Spiro made his name defending a long list of embattled celebrity clients, including Jay-Z, Alec Baldwin and, most recently, Elon Musk, for whom he serves as a personal lawyer.