Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches.

Guanine quadruplexes (G-quadruplexes or G4s) are unusual nucleic acid structures with distinct biological and chemical functions. They have occupied significant attention in the nucleic acid world ...

The more researchers examine RNA, the more surprises they continue to uncover. What have we learned about RNA structure and function so far? Although RNA is a single-stranded molecule, researchers ...

When people eat, they ingest the nucleic acids that reside in all living things. The compounds in these acids could inhibit ...

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

The findings were published on January 7 in the journal Nucleic Acids Research in a paper titled "Single-molecule ... The team discovered that IPMK binds directly to SRF, altering the ...

Scientists detail technique to camouflage immunostimulatory nucleic acid nanofibers via dna aptamer functionalization, thereby dramatically expanding possibilities for employing structures as vaccine ...