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Scientists at The Wistar Institute have discovered how a key protein from the Epstein-Barr virus (EBV), EBNA-LP, ...
Look inside a brain cell with Huntington's disease or ALS and you are likely to find RNA clumped together. These solid-like clusters, thought to be irreversible, can act as sponges that soak up ...
No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.
With more than 2,100 members, EMBO stands for excellence in the life sciences. It accepts outstanding researchers who are nominated and elected by its members on the basis of their exceptional ...
The analysis and visualization of nucleic acids (RNA and DNA) is playing an increasingly important role due to their fundamental importance for all forms of life and the growing number of known 3D ...
Natural signaling networks can act as bandpass filters to interpret external stimuli within defined concentration ranges for differential cellular activities. Replicating such a bandpass filtering ...
The laboratory of Ege Kavalali, professor and chair of the Department of Pharmacology, published a paper in Nature ...
Nitrogen is an essential component in the production of amino acids and nucleic acids—both necessary for cell growth and ...
Minchin, S. and Lodge, J. (2016) Understanding Biochemistry Structure and Function of Nucleic Acids. Essays in Biochemistry Journal, 63, 1010-1017.
In addition, non-canonical structures are often associated with DNA damage and genomic instabilities, which are common mechanisms for certain cancers. To be precise, secondary nucleic acid structures ...
Scientists detail technique to camouflage immunostimulatory nucleic acid nanofibers via dna aptamer functionalization, thereby dramatically expanding possibilities for employing structures as vaccine ...