That production has come on an offense that has been without starting quarterback Brock Purdy (toe), tight end George Kittle ...

Thus far, the battle-tested 49ers are atop the NFC West, and they have two wins with backup quarterback Mac Jones, who ...

Before the season began, I projected the Niners at 10-7 and the final wild card in the NFC. Three weeks in, they are undefeated, but without Nick Bosa.

Bryce Huff • DE With Nick Bosa and Mykel Williams (for a stretch) out, Huff stepped up in a big way. Not only did he get a ...

The San Francisco 49ers struggled in their home opener, but they left Week 3 with a win vs. the Arizona Cardinals. Here are ...

The 49ers face challenges as Nick Bosa sustains a season-ending injury. Discover the latest roster changes and updates.

Shanahan was asked whether third-stringer Adrian Martinez would get the reps with both Purdy and Jones injured. Shanahan said ...

Adam Schefter reported 49ers wide receiver Ricky Pearsall missed the Niners’ Wednesday practice due to a knee injury.

The Texans released CJ Gardner-Johnson and in the aftermath, some insiders and fans urged the 49ers to sign him.

Jauan Jennings will join Brock Purdy on the 49ers’ sideline and not play in today’s home opener against the Arizona Cardinals ...

NEW ORLEANS, LOUISIANA – SEPTEMBER 14: Mac Jones #10 of the San Francisco 49ers is congratulated by Christian McCaffrey #23 ...

San Francisco 49ers defensive end Nick Bosa is believed to have a suffered a torn ACL in Sunday's win over the Arizona Cardinals, NFL Network Insider Ian Rapoport reported Monday.