The review synthesizes evidence on whether Alzheimer’s disease medications can improve neurocognitive outcomes in children ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

BUFFALO, N.Y. – Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders.

D epression can be challenging to treat. Typical antidepressants, which affect levels of chemicals in the brain involved in mood regulation, have been evolving for decades. But recent findings ...

Department of Physiology, Kochi Medical School, Kochi University, Kochi, Japan Although animal behavior is influenced by neuromodulatory signals, the underlying mechanism remains elusive. The ventral ...

As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At Cold Spring Harbor Laboratory (CSHL), scientists have turned their attention to the tiny pores ...

The final, formatted version of the article will be published soon. N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis (NMDARE) is an autoimmune disorder in which approximately 25% of ...

A drug originally developed to treat Alzheimer’s disease may also help teenagers with autism improve their communication skills, according to a new study. The drug, called memantine, works by blocking ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. The previous evidence for NMDARs containing N1, N2, and N3 ...

ScRNA-seq and immunoprecipitation analysis of NMDAR subunits co-expression and co-assembly patterns in the brain. a Structural analysis of extracellular domains of N2A or N3A subunits. The COM of R1 ...