We have identified a macrophage population "Mrep" that plays an essential role in muscle repair. However, in Fibrodysplasia ossificans progressiva (FOP), Mrep functions as a pathogenic cell that ...

Traumatic muscle injury can be associated with volumetric muscle loss (VML), often leading to permanent functional loss.

Musculoskeletal disorders are a primary cause of disability worldwide, especially in aging societies like Japan. As individuals age, reductions in muscle mass and physical activity weaken the body's ...

Japan has approved two stem cell-based therapies for treating Parkinson's disease and heart failure in a world first, through ...

Sarcopenia—reduced muscle mass, strength, and function—is often associated with aging and frequently impacts quality of life in the elderly. Individuals with sarcopenia are also prone to further ...

Muscle cells contain their own circadian clocks and disrupting them with shift work can have a profound impact on aging, according to the results of a preclinical study carried out by Jeffrey Kelu, ...

DECEMBER 3, 2025—(BRONX, NY)—Two related studies published today in Nature Metabolism show that a specialized intracellular recycling mechanism—chaperone-mediated autophagy (CMA)—is essential for ...

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce ...