US stock futures rose on Wednesday as Wall Street digested a rotation out of Big Tech into more defensive corners of the market and awaited a key House vote that could end the longest government shutdown in US history.

Stock index futures surged Monday as reports surfaced that Senate negotiators struck a stopgap deal to end the record-breaking government shutdown. Here are four stocks to watch on the day:

Metsera Inc (NASDAQ: MTSR) shares dipped 15% to $70.68 in pre-market trading. Pfizer Inc. (NYSE: PFE) secured a $10 billion deal to acquire obesity drug developer Metsera, beating out Novo Nordisk A/S (NYSE: NVO) after a heated bidding war that captivated Wall Street.

US stock futures leaned lower on Tuesday amid a revival in AI worries, slipping back from a rally fueled by optimism that Washington may soon end the record-breaking government shutdown. Testing that faith,

Nasdaq 100 slips pre-market as AI stocks retreat. Nvidia, CoreWeave fall after Monday’s rally. Traders question if the bounce has real staying power.

The futures are trading higher as the new week begins, with most investors and traders relieved that last week has come to a close.  Hopes that an end to the Government shutdown in Congress is driving the futures higher this morning.

Stock index futures were barely changed on Tuesday, as investors awaited any recent updates about the possible end of the U.S. government shutdown. S&P 500 futures ( SPX) -0.1%, Nasdaq 100 futures ( US100:IND) -0.2% and Dow futures ( INDU) were flat.

Futures for Canada's main stock index slumped to a two-month low on Monday as oil prices dropped, while all eyes were on a federal election where Prime Minister Justin Trudeau could cling to power but looked set to lose his bid for a majority.

The S&P 500 Index ($SPX) (SPY) today is up +1.10%, the Dow Jones Industrials Index ($DOWI) (DIA) is up +0.55%, and the Nasdaq 100 Index ($IUXX) (QQQ) is up +1.81%. December E-mini S&P futures (ESZ25) are up +1.