Abstract: Mast cells play an important role in the development of allergic disease, and RBL-2H3 cells, a subsystem of rat basophilic leukocytes (RBL), can express many of the properties and functions ...

Wet age-related macular degeneration (AMD) is characterized by choroidal neovascularization (CNV), yet current anti-VEGF therapies are ineffective in many patients. This study investigates the role of ...

Credit: Getty Images Cholinergic urticaria is induced by an increase in core body temperature and characterized by pinpoint wheals that typically resolve spontaneously within 15 to 60 minutes. The ...

Please provide your email address to receive an email when new articles are posted on . Evidence of systemic mast cell activation in the PROSPECTOR study was split into three categories. A REMA score ...

CONDITION DEFEAT HER. I SPENT A LOT OF TIME KIND OF CALMING AND REGULATING MY NERVOUS SYSTEM. IN SOME WAYS, 26 YEAR OLD CAROLINE CRAIG QUINN’S MORNING LOOKS LIKE MANY OF OURS. A LITTLE YOGA, A QUIET ...

Rhinitis, a prevalent inflammatory condition of the upper airway, imposes a substantial global health burden. While current pharmacotherapies alleviate symptoms, they are ineffective in restoring ...

In dogs, mast cell tumors are the most common malignant skin tumors, accounting for approximately 16–21% of all skin cancers. These tumors can appear anywhere on the body but are most frequently found ...

A recent study led by Johns Hopkins researchers across multiple departments, working with colleagues at UTHealth Houston, uncovers a mechanism that fuels post-stroke inflammation, revealing a new path ...

Scientists show that prenatal stress reshapes fetal mast cells and sensory neurons, creating a fragile skin barrier that sparks early-life eczema in mice. Study: Maternal stress triggers early-life ...

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause ...

SOUTH SAN FRANCISCO, Calif., Aug. 21, 2025 (GLOBE NEWSWIRE) -- Septerna, Inc. (Nasdaq: SEPN), a clinical-stage biotechnology company pioneering a new era of G protein-coupled receptor (GPCR) drug ...

Bone disease is a significant yet often underrecognized comorbidity in patients with systemic mastocytosis. Diagnosing and managing bone health in this patient population is challenging due to ...