Several animal models have been developed and characterized, and they have been invaluable for identifying and characterizing mechanisms of protective immunity to M. tuberculosis. However, the ...

WEST LAFAYETTE, Ind. - Scientists have discovered the mechanism that hijacks the immune system's response to tuberculosis, revealing an important new drug target for the disease that kills more than 1 ...

Immunotherapy. 2012;4(6):629-647. This review introduces the disease, particularly the complex interaction of M. tuberculosis with the host's immune system, as background to understanding the ...

Branches are colored according to the M. tuberculosis complex lineage: pink for lineage 1, blue for lineage 2, purple for lineage 3, and red for lineage 4. Discrete heat maps next to the phylogeny ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Mycobacterium tuberculosis (MTB) and Mycobacterium avium complex (MAC) are two distinct types of bacteria that can cause infections in the lungs and other parts of the body. Belonging to the same ...

Tuberculosis (TB) is the world’s deadliest infectious disease. In 2023, about 10.8 million people contracted TB, and 1.25 million people died from it, according to the World Health Organization.

Tuberculosis (TB) latency involves infection with the bacteria that also cause active TB. However, people with TB latency do not have symptoms. Treatment for TB latency can help reduce the risk of ...

What do a cow, a deer, and a hunter have in common? The answer in certain parts of Michigan may be Mycobacterium bovis, the bacteria that causes bovine tuberculosis, if hunters are not careful. As ...

Untreated tuberculosis may result in several long-term complications, such as permanent lung damage. It’s vital for the condition to be treated early to prevent the infection from traveling to other ...

It sailed in stealthily, like the fog. Carried by the hordes eager to grab gold, tuberculosis began a frightening, infectious march through San Francisco in the mid-1800s. Known then as consumption, ...