Candidate profiles include HCC, liver metastases, and hepatic adenomas, including multifocal disease and stage IV patients who might otherwise be excluded from liver-directed interventions. Outpatient ...

Approximately 25% of patients with colorectal cancer present with metastatic disease to the liver at diagnosis, and about 50% develop liver metastases at some point during the course of the disease.

This timely and fundamental study introduces a human iPSC-based co-culture system that models Kupffer cell-hepatocyte interactions and aims to recapitulate liver-specific immune-parenchymal dynamics.

Background: Single-ventricle congenital heart disease is a rare and lethal cardiac abnormality that disrupts normal circulation in neonates. The cavopulmonary redirection of blood in these patients ...

Liver fibrosis may be diagnosed and staged — no fibrosis (stage F0), mild fibrosis (F1), significant fibrosis (F2), advanced fibrosis (F3), and cirrhosis (F4) — with the use of clinical parameters and ...

Abstract: Nonalcoholic fatty liver disease represents a major global burden of liver-related illnesses. Its progressive form, known as nonalcoholic steatohepatitis (Progressive NASH), is closely ...

Hepatic pseudolipoma is a relatively rare benign tumor of the liver in primary hepatic lesions and is characterized by focal fat around the liver capsule. It typically affects older adult men. In this ...

Cholangiocytes are highly specialised cells participating in the pathobiology of various liver diseases and recognised to play a crucial role in response to liver injury. Cholangiocytes exhibit ...

Semin Liver Dis. 2013;33(3):236-247. Focal nodular hyperplasia has no malignant potential and usually remains stable or decreases in size over time. Less than 20% of patients with FNH develop symptoms ...

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