Lineup notes on who's in, who's out and which fantasy football starters are questionable for this weekend's games.

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of ...

Linebacker Dre Greenlaw was back at practice in a limited capacity on Wednesday following his Week 15 regular season debut.

Don’t miss episodes of Fantasy Football Happy Hour with Matthew Berry and Rotoworld Football Show all season long for the latest player news, waiver wire help, start/sit advice, and much more.

American safety Ugo Amadi's performance in the 14-11 win over the New York Giants played a crucial role in keeping the 2025 ...

Rookie running back Isaac Guerendo scored from a yard out with 1:39 left in the first quarter and the 49ers are up 14-0 at Levi’s Stadium. Guerendo set up his score with a 27-yard catch from ...

LATEST Dec. 8, 4:15 p.m. New 49ers starting running back Isaac Guerendo didn't even complete his first game as the feature back before exiting with an injury, continuing a nightmare-like season ...

With Christian McCaffrey and Jordan Mason on the injured reserve, Sunday's contest against the Chicago Bears marked the first start for San Francisco 49ers rookie running back Isaac Guerendo.

Backup running Ameer Abdullah is in line to get an increased workout with White and Mattison ... the 49ers' running game will likely center on rookie Isaac Guerendo, who rushed for 99 and 85 ...

Entering a do-or-die matchup vs. the Chicago Bears this Sunday, the San Francisco 49ers are banking on rookie running Isaac Guerendo to fill the shoes left by reigning Offensive Player of the Year ...