RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until ...

Isaac Guerendo brought an uncommon back story to ... but didn’t make his first start until the Cardinals’ Holiday Bowl matchup with USC; then Guerendo ran for 161 yards on 23 carries.

SANTA CLARA — When Isaac Guerendo trots onto the field with the ... and it came in his final college game at Louisville. Against USC in the Holiday Bowl, Guerendo carried 23 times for 161 ...

Isaac Guerendo is likely to take the place of Christian McCaffrey ... In the 2023 Holiday Bowl, Guerendo rushed for a season ...

SANTA CLARA — When Isaac Guerendo trots onto the field with the ... and it came in his final college game at Louisville. Against USC in the Holiday Bowl, Guerendo carried 23 times for 161 ...

San Francisco 49ers rookie running back Isaac Guerendo sustained a foot injury and was questionable to return in Sunday's matchup with the Chicago Bears. More News: Chargers Make Game-Time ...

Guerendo (foot, hamstring) has been ruled out for Sunday's game at Miami, Matt Maiocco of NBC Sports Bay Area reports. Guerendo didn't practice this week and thus appears in danger of missing time ...

The San Francisco 49ers running back Isaac Guerendo is dealing with a hamstring injury and is unlikely to play Sunday at the Miami Dolphins, a source told ESPN's Adam Schefter on Thursday.

Entering a do-or-die matchup vs. the Chicago Bears this Sunday, the San Francisco 49ers are banking on rookie running Isaac Guerendo to fill the shoes left by reigning Offensive Player of the Year ...

Isaac Guerendo is a largely untested talent. He spent five years in college and was mostly unproductive until his final year, where he still failed to surpass 900 rushing yards. Nevertheless ...

Isaac Guerendo is expected to step in as the San ... Guerendo rushed for a season high 161 yards and three touchdowns, on 23 carries, but USC won 42-28. Guerendo finished with 810 yards and ...