ESPN’s Adam Schefter reported that San Francisco 49ers running back Isaac Guerendo will try to play tonight against the Los ...

The 49ers went after Guerendo in the draft because he reminded them a lot of Mostert, whom they'll face Sunday in Miami.

The San Francisco 49ers are banking on rookie running Isaac Guerendo to fill the shoes left by a former Offensive Player of ...

As the first quarter wound down in his second NFL game, San Francisco 49ers running back Isaac Guerendo trotted ... No. 129 overall -- on Guerendo in April's NFL draft. The idea was to add the ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.

Christian McCaffrey and Jordan Mason are both injured, so Guerendo is set for his chance as San Francisco’s starting running ...

Should Guerendo start as expected Sunday, it will be just his second start as a running back since he was in the fourth grade ...

San Francisco 49ers rookie Isaac Guerendo didn't transition to playing running back until he arrived at Wisconsin. Before ...

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Curious to know about 49ers RB Isaac Guerendo‘s injury? The standout rookie has drawn attention for his breakout performances ...