Surely, inflammation is half a billion years old, since even the lowly starfish may experience it. Virtually every human being who ever lived has suffered from it, perhaps dozens or hundreds of times.

Our immune system is armed with an array of defenses designed to detect and eliminate harmful threats. One of its most powerful defense mechanisms is the complement system—a group of proteins that ...

IBD research, for all its sophistication, has been searching under the lamppost — sequencing, mapping and quantifying what can be seen. But the key may lie in the park, in the unseen intersections of ...

Chronic alcohol use accelerates Alzheimer’s disease (AD) progression by intensifying oxidative stress, neuroinflammation, and ...

Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, ...

Researchers at the University of California, Irvine, have uncovered an unexpected molecular partnership that reshapes ...

Pharmacological activation of LANCL2 provides CNS immunometabolic support for the restoration of cognitive function markers in a mouse model of Alzheimer’s disease. Pharmacological activation of ...