The brain extracellular matrix plays a critical role in synaptic plasticity, including experience/adaptive-based changes in ...

More than 100 clinical trials put stem cells for regenerative medicine to the test. It’s a turning point for a field beset ...

Scientists have developed human stem cell models containing the notochord, a critical tissue that guides spine and nervous system formation during embryonic development.

For the first time, the notochord a tissue in the developing embryo that serves as a navigation system, telling cells where to build the spine and nervous system (the trunk) has been included in human ...

Within minutes of fertilization, the egg of a fruit fly becomes a scene from the battle of the sexes. The egg attacks and destroys the cellular “power plants,” or mitochondria, from the sperm that had ...

Scientists have generated human stem cell models which contain notochord -- a tissue in the developing embryo that acts like a navigation system, directing cells where to build the spine and nervous ...

Researchers have made a significant advancement in studying early human development by successfully creating a lab-grown notochord, a key structural component in vertebrates. This model, based on a ...

They grew their organoids in a lab using human induced pluripotent stem cells from healthy donors and patients with MS and ...

Researchers discovered that neurons in the medial frontal cortex encode abstract progress through sequences of behaviors, enabling flexible task mapping and rapid adaptation to new structures.

In this manuscript, Yao et al. present solid evidence to show that MnMYL3 may serve as a receptor for NNV via macropinocytosis. This manuscript is valuable for understanding the molecular mechanisms ...

Briola and co-authors determined the structure of the human CTF18 clamp loader bound to PCNA to high resolution, analyzed the structure, and tested a new mechanism involving a human-specific Ctf18 ...

Now, they’re proposing something far more ambitious: creating complete virtual copies of human cells that can be studied, ...