Michael Gotthardt at the Max Delbrück Center and collaborators are developing a drug to treat a common type of heart failure characterized by impaired cardiac filling. In a recent study, his group and ...

A hidden atrial dysfunction may raise stroke risk in people with transthyretin amyloid cardiomyopathy (ATTR-CM); however, a noninvasive assessment tool may help identify those at increased risk, ...

A new experimental therapy helps restore the heart’s flexibility in models of stiffened heart failure. Michael Gotthardt and his colleagues at the Max Delbrück Center are working with U.S. researchers ...

A naturally occurring gene called Cyclin A2 (CCNA2), which turns off after birth in humans, can actually make new, functioning heart cells and help the heart repair itself from injury, including a ...

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is ...

Uncertainty surrounding how truncated titin proteins (TTNtvs) cause dilated cardiomyopathy (DCM) and peripartum cardiomyopathy (PPCM) led to investigations that could better inform therapies for these ...

Although cardiomyopathy might sound like a shorthand synonym for cardiovascular disease, there are important distinctions you should know about if you or a loved one is experiencing any issues with ...

Heart failure (HF) is one of the leading causes of death and disability worldwide, affecting millions of people and placing ...