Human immunodeficiency virus type 1 (HIV-1 ... provide a potential explanation for the evolution of the unique HIV capsid structure: its conical shape might be necessary to break the nuclear ...

They graphically represent the life cycle of HIV-1, from the initial binding of the viral particle onto a host cell (Viral Entry), through insinuation into the host cell's nucleus to spark the ...

Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.

To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red).

The human immune deficiency virus (HIV) first entered public consciousness ... and they form a new structure," said Chelico. "APOBEC proteins are part of a natural defense system against viruses ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ... So we can't really get a good structure of it." ...

What about viruses? Would you consider them living or nonliving? Let’s look closely at the life cycle of the human immunodeficiency virus (HIV) – the virus that causes AIDS – to find out. This ...

A retrovirus is an infectious agent belonging to the RNA virus ... HIV-1 TAR RNA plays key roles in viral replication, transcription, and translation. Here, Bou-Nader et al., portray the structure ...

"An effective HIV cure strategy depends on successfully targeting viral reservoirs, the virus-infected cells in which the virus can persist and cause long-term complications," said Dr. Montaner.

Figure 1: Structural organization of Gag-Pol polyprotein in HIV-1. We speculated that the ... for the regulation of protease activity in the virus replication cycle. Figure 2: Protease precursor ...