Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.

The resulting complex of viral cDNA and virion proteins, now referred to as the pre-integration complex (PIC), is transported to the nucleus (Fig. 1). Figure 1: Models of flap-dependent HIV ...

HIV-1 Gag directs virion formation and budding from host cell membranes by interacting with critical membrane microdomains. At least 253 cellular proteins from multiple cellular pathways have been ...

Dr. Ochsenbauer-Jambor investigates the role of DC-SIGN in the capture and trans-infection of HIV-1 with special emphasis on virion internalization pathways and the acquisition of selective ...

The development of HIV resistance to highly active antiretroviral therapy (HAART) drugs and the long-term toxicity of such medicines has resulted in HIV/AIDS researchers believing that re ...